Five best friends, all married, decide to share a loft apartment. In this loft they meet their mistresses and conquests. Everything seems perfect, until one morning the body of an unknown young woman is found in the loft. The group of friends begin to suspect each other and it soon becomes clear that they know far less about each other than they had initially thought.

A rich American couple, a family of Dutch criminals, a French gay couple, a working class family from Germany and an illegal Moroccan youth and his kid brother, are all in Amsterdam, each with their own story. Different reasons make their paths intertwine, leading to a dramatic climax that changes their lives for ever.